P31.17: First and/or second trimester screening for Down syndrome: a single-center experience
نویسندگان
چکیده
منابع مشابه
Screening for Down syndrome in the second trimester of pregnancy.
Antenatal screening for fetal anomalies has provided women and their partners with information to make reproductive choices based on the risk of serious chromosomal or structural defects since the 1990s. Alternative tests include first-trimester screening (combined ultrasound and maternal serum markers), second-trimester maternal serum markers and noninvasive cell-free DNA testing. The recent r...
متن کاملFirst- and second-trimester evaluation of risk for Down syndrome.
OBJECTIVE To investigate the differences in costs and outcomes of Down syndrome screening using data from the First and Second Trimester Evaluation of Risk (FASTER) Trial. METHODS Seven possible screening options for Down syndrome were compared: 1) Triple Screen-maternal serum alpha fetoprotein, estriol, and hCG; 2) Quad-maternal serum alpha fetoprotein, estriol, hCG, and Inhibin A; 3) Combin...
متن کاملCombining first and second trimester markers for Down syndrome screening: think twice.
AIMS This study compares different screening strategies for the detection of Down syndrome and considers practical implications of using multiple screening protocols. METHODS The performance characteristics of each screening strategy were assessed based on datasets of Down syndrome (n=11) and unaffected pregnancies (n=1006) tested in both first and second trimester, as well as data from first...
متن کاملRole of second-trimester genetic sonography after Down syndrome screening.
OBJECTIVE To estimate the effectiveness of second-trimester genetic sonography in modifying Down syndrome screening test results. METHODS The First and Second Trimester Evaluation of Risk (FASTER) aneuploidy screening trial participants were studied from 13 centers where a 15- to 23-week genetic sonogram was performed in the same center. Midtrimester Down syndrome risks were estimated for fiv...
متن کاملNuchal translucency measurement in first trimester Down syndrome screening.
(1) Approximately three in every four fetuses with Down syndrome have increased nuchal translucency (NT), which is a larger than normal build-up of fluid at the back of the neck. (2) The ultrasound measurement of NT between 11 and 14 weeks' gestation, in combination with the mother's age and the levels of placental biochemical markers in her blood, can be used to detect approximately 84% of fet...
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ژورنال
عنوان ژورنال: Ultrasound in Obstetrics and Gynecology
سال: 2007
ISSN: 0960-7692
DOI: 10.1002/uog.4787